Varicose veins are localized lesions caused by blood stagnation and weakness of the venous walls, and skin ulceration is a serious complication of varicose veins. For skin ulcers caused by varicose veins, clinically commonly used drugs include oral and topical drugs.1. Oral drugs: For skin ulcers caused by simple varicose veins, clinically commonly used drugs such as Mizling and Xulodex are taken orally. If the patient has deep vein thrombosis, the skin ulcer should be treated based on the treatment of deep vein thrombosis, usually oral rivaroxaban, warfarin, etc.; 2. Topical drugs: topical drugs such as epidermal growth factor and myogenic cream are often used clinically to promote ulcer crusting, and some doctors also use topical drugs containing silver ions, such as Yinershu, to treat local skin ulcers. For smaller skin ulcers, surgical treatment of varicose veins is often performed along with medication to ligate or embolize the traffic veins, which can be a radical cure. For larger skin ulcers if the effect of drug therapy alone is poor, implantation or flap surgery can be used along with ligation of the communicating branch for more effective results. Patients with skin ulcers with varicose veins must be careful to avoid hot water foot baths and local infections, otherwise the treatment effect will be affected.