Rheumatic diseases are a group of diseases that mainly affect joints, bones, muscles, blood vessels and related soft or connective tissues, most of which are autoimmune diseases. Broadly speaking, all diseases that cause bone and joint, muscle pain can be classified as rheumatic diseases, which have included more than 200 kinds of diseases, including infectious, immune, metabolic, endocrine, genetic, degenerative, tumor diseases and other causes, most of which can affect the systemic system. Clinically, many rheumatology patients have seen the wrong department. Rheumatic disease manifestations are diverse, the following 10 more common, once the emergence of the recommended rheumatology and immunology consultation, so as not to delay treatment. 1, joint swelling and pain Most rheumatic immune diseases have joint symptoms, mainly manifested as joint swelling or pain, which can be accompanied by redness and burning of the skin around the joints. If a middle-aged man has sudden redness and hot pain in the metatarsophalangeal joint of the first thumb after drinking and eating seafood, it may be gout; wandering pain in large joints throughout the body should be considered rheumatic fever; women with joint pain, if accompanied by hair loss, mouth ulcers and other discomforts, need to be alert to the possibility of systemic lupus erythematosus. If the pain is mainly in small joints (wrist joints, finger joints), rheumatoid arthritis is more likely, and it is recommended to consult a specialist in rheumatology and immunology to clarify the diagnosis. 2, morning stiffness In the early morning after waking up, low back pain, joint stiffness for a long time after resting, such as the feeling of adhesive, gradually reduced after appropriate activities is called morning stiffness. Middle-aged women with morning stiffness should consider rheumatoid arthritis, and young men with morning stiffness should suspect ankylosing spondylitis. 3. Skin and mucous membrane symptoms Unexplained rashes, skin irritation after sun exposure, mouth ulcers, vulvar ulcers, skin nodules, erythema, etc. may also be rheumatic diseases. For example, systemic lupus erythematosus may appear as a butterfly rash on the face, oral ulcers; hardening of the skin should be considered as scleroderma; recurrent oral ulcers in young people with vulvar ulcers or ophthalmia, skin erythema may be leukoplakia, etc. 4, unexplained fever Infection, tumor, rheumatism are the three common causes of unexplained fever. If the conventional anti-infection treatment is ineffective and there is no obvious evidence of tumor, attention should be paid to the possibility of rheumatic diseases. 5, Raynaud’s phenomenon Refers to the hands or feet turning white and then purple when cold or emotional change, turning red after warmth or emotional stability, and finally turning to normal color, which may be scleroderma, systemic lupus erythematosus various vasculitis, etc. Some people keep thinking they are frostbite, in fact, frostbite does not flare up in spring, autumn or summer, and it is too late to look at it again when internal organs are involved oh. 6, dry mouth, dry eyes, dry skin This is likely to be dry syndrome, dry mouth is mainly manifested as less saliva, daily need to drink a lot of water, serious rampant dental caries, early loss of teeth; dry eyes is mainly manifested as dry eyes, “want to cry no tears” feeling, must be many times a day to point eye drops to relieve; dry skin is manifested as less sweating, skin flaking, itching, etc. 7, muscle pain, weakness If there is muscle pain and weakness in the limbs, difficulty in standing up after squatting, difficulty in raising the arms, or with purple around the eyes, rash on the front and back of the chest, blood sampling biochemistry found to be elevated muscle enzyme profile, etc., may be dermatomyositis, polymyositis, etc. 8, low back pain and alternating hip pain Mainly characterized by increased symptoms at rest, especially low back pain more common in the second half of the night, will be reduced after activity, stiffness when getting up, sometimes accompanied by knee and ankle swelling and pain, if there is a family history of ankylosing spondylitis, iritis, etc., it is recommended to go to the Department of Rheumatology and Immunology to check the HLA-B27 gene and imaging to exclude ankylosing spondylitis. 9. Multi-system or multi-organ damage Mainly manifested as multi-system damage of heart, liver, kidney, lung, brain, skin, joints, etc. Most commonly seen in diseases such as systemic lupus erythematosus, systemic vasculitis, systemic sclerosis, etc. Multiple organ problems, if there is no obvious cause, need to be highly alert to rheumatic diseases. 10, unexplained weakness Some people are very weak, originally thought tired, but on second thought, recently there is no super-intensive labor and exercise, no delay in sleep, or rest for a period of time, but weakness or has been bad. Some of the early manifestations of rheumatic diseases as weakness, of course, it is still recommended to go to the rheumatology specialist consultation to clarify the condition of it, there is absolutely no need to be in the right place, to their own medical treatment.