Most patients with autoimmune liver experience significant systemic symptoms. Autoimmune liver refers to autoimmune liver disease, which is a group of liver and gallbladder injurious diseases caused by abnormal autoimmune function in the body due to genetic or environmental factors. After the disease progresses, due to abnormal liver function, detoxification and metabolism function is reduced, the body’s immune ability is reduced, resistance to the outside world is reduced, there will be fatigue, drowsiness, itchy skin, jaundice, loss of appetite and other symptoms. As well as may be accompanied by fever, rash, osteoporosis, diarrhea and other symptoms. When the patient appears autoimmune liver disease, should actively carry on the treatment, commonly used with prednisone and azathioprine combined treatment, such as the patient appears itchy skin can also follow the doctor’s instructions to apply emollient and kauleidenamine and so on. Patients with autoimmune liver disease should go to the hospital in time for examination and choose the appropriate drugs for treatment.