Patients appear in the near-death stage, suggesting that the condition is extremely critical and death may occur at any time. The common clinical manifestations are mainly as follows: First, sigh-like breathing is manifested by the patient’s head tilting forward when inhaling and tilting back when exhaling, which is a manifestation of the patient’s extremely weakened lung function and often suggests extreme ischemia and hypoxia in the patient’s body. Second, persistent coma, call does not answer, the patient because of the inability to take in enough energy, the body can only reduce the body’s energy consumption through coma or coma to maintain life as much as possible. Third, the limbs are obviously swollen and accompanied by a large amount of ascites, which is due to the extreme malnutrition of the patient, and the water in the blood vessels seeps into the tissue interstices, manifesting as swollen limbs and bulging stomach.