The feeling of fullness after eating a little may be related to indigestion, pyloric obstruction, stomach cancer and other diseases. 1. Indigestion: due to insufficient gastric motility, the peristalsis of intestines and stomach slows down, food can not be fully digested and absorbed in the gastrointestinal tract, and the process of food emptying will be relatively prolonged, which leads to the storage of food in the stomach for a long period of time, resulting in a feeling of fullness. 2. Pyloric obstruction: some patients have pyloric obstruction, which leads to the gastric contents cannot be discharged in time, and the food stays in the stomach for a long time, and the main manifestation is the feeling of fullness and belching in the upper abdomen. 3. Stomach cancer: stomach cancer is a tumor of gastrointestinal tract, and when stomach cancer enters the advanced stage, it will affect the digestive function of stomach, and there may be loss of appetite, feeling of fullness and so on. If the above situations occur, you should go to the hospital in time and get symptomatic treatment under the doctor’s guidance.