Alzheimer’s disease does not usually cause mania, but manic manifestations can occur in the late stages of Alzheimer’s disease, which is just a process of the disease and is different from what is conventionally thought of as mania. Alzheimer’s is a series of clinical manifestations due to intracranial nerve cell degeneration, which can occur from early depression and anxiety to late mania. However, it is a clinical manifestation due to the decline of cortical function, not mania. In medical science, mania belongs to the category of psychiatric disorders, which is due to neurotransmitter dysfunction and then manic performance, and mania treatment is mainly through psychiatric medication. However, Alzheimer’s disease is treated with mania while restoring cognitive impairment in old age is the main treatment. Therefore, when mania occurs in the late stage of Alzheimer’s disease, it should not be considered as a manic patient sent to a psychiatric hospital for treatment, which may cause more mental stress to the patient and is unfavorable to the later recovery.