The patient’s hepatitis B DNA suggests more than 10^3IU/mL, at this time the patient is considered to have viral replication, usually mild replication, whether the treatment needs to be combined with other indicators, at this time the patient also needs to draw blood to check the three systems of hepatitis B, liver function, liver ultrasound, etc., to see whether the patient has liver function damage and whether there is cirrhosis. If liver function is impaired or accompanied by cirrhosis, active antiviral treatment should be considered. Oral antiviral drugs, such as tenofovir and entecavir, or interferon injection can be chosen. Generally speaking, oral drugs need to be taken for a long time, and cannot be stopped in the middle of the course, which may cause rebound of viral replication and sharp decline of liver function. In addition, for interferon injection patients, it takes about half a year to a year of injection, through the interferon injection, some patients will turn into negative or carriers. During the treatment period, patients should pay attention to more rest, do not stay up late, do not labor, especially do not drink alcohol. Because alcohol is more damaging to the liver, if patients with hepatitis, their liver function reserve is generally poor. If the patient drinks alcohol, it will further cause the patient’s liver insufficiency, as well as the possibility of liver failure.