Avanafil tablets and sildenafil tablets belong to the same class of drugs, but each has its own characteristics. For patients, the one that suits them is the best. Avanafil tablets and sildenafil tablets are both phosphodiesterase type 5 inhibitors, clinically used in the treatment of male erectile dysfunction. You can’t say which one is better or worse, but the one that suits you is the best. The physician will choose the drug according to the patient’s specific situation for treatment. The similarities and differences between the two are shown in the following aspects. 1. Avanafil tablets last longer than sildenafil tablets. The half-life of the two is different, the half-life of sildenafil tablets is 2~4 hours, and the half-life of avanafil tablets is 4~6 hours. 2. The metabolism of the two drugs is basically the same, mainly through the feces form of excretion, a small part of the excretion from the urine. 3. The adverse reactions of the two drugs are different, sildenafil tablets have a certain incidence of visual abnormalities, while the side effects of avanafil tablets have no visual abnormalities, and other adverse reactions are similar. 4. The maximum plasma concentration of the two drugs is different from the peak time. Generally, sildenafil tablets take about 1 hour, while avanafil tablets can reach the peak in 15 minutes at the earliest.