Postural care is a very important part of the developmental care of preterm infants. It is usually necessary to give different positions according to the condition of the preterm infant, which has the effect of relieving adverse stimuli, promoting sleep, keeping warm, facilitating feeding and promoting the development of the preterm infant. In addition, preterm infants, because of their soft heads, can suffer from head deformation when they are in a certain position for a long time, which can take a long time to recover and even leave an asymmetrical head shape. Understanding the effects of different positions on infants can help us determine the appropriate position to give to the child at different times. The status of 26 infants in different positions was observed, including indicators of body temperature, respiration, and the amount of milk left in the stomach. Effect on body temperature Body temperature was better maintained in the left-sided, right-sided and prone positions than in the supine position. This is due to the fact that in the lateral and prone positions, the preterm infant’s skin is less exposed than in the supine position, and it is more comfortable to be wrapped tightly and the activity is reduced, so the lateral and prone positions are good for maintaining the body temperature of the preterm infant. Maintaining the body temperature of preterm infants helps to reduce the consumption of energy and oxygen, which can promote the weight gain of preterm infants. Effects on respiration When preterm infants were in supine, prone, left-sided and right-sided positions, the respiratory rate gradually decreased from an average of 55 breaths/min in the prone position to 49 breaths/min, and respiration gradually stabilized, and there was no occurrence of apnea, which shows that the prone position is conducive to ventilation, while there is no significant difference between the remaining positions. Effect on the amount of residual milk in the stomach Compared with supine and left lateral positions, right lateral and prone positions were favorable to promote gastric emptying. The left lateral position, on the other hand, reduces gastroesophageal reflux. It can be seen that different positions are reasonably given according to the needs of preterm infants to promote their development.