As the drugs need to be metabolized and excreted by the liver and kidneys, there is no absolute antihypertensive drug that does not harm the liver and kidneys, and the drugs that cause less damage to the liver and kidneys are angiotensin-converting enzyme inhibitors, angiotensin 2-receptor antagonists and calcium antagonists, and beta-blockers.
Captopril is an angiotensin-converting enzyme inhibitor, and valsartan is an angiotensin 2 receptor antagonist antihypertensive drug, these two drugs in the lowering of blood pressure at the same time also have a certain degree of protection for the kidneys, belonging to the less liver and kidney damage to the drug.
In addition, calcium antagonists such as nifedipine and other receptor blockers such as metoprolol and other antihypertensive drugs also have less damage to the liver and kidneys.
However, the drug does not exist absolute effective safety, need to strictly follow the doctor’s instructions standardized use, choose the most suitable for their own antihypertensive drugs. Adverse reactions such as nausea, abdominal pain, skin rash, etc. should be promptly consulted, drug allergy is prohibited.