Small cell lung cancer is the most malignant type of lung cancer. Its cell multiplication time is only 33 days, which is significantly shorter than that of squamous lung cancer (98 days) and adenocarcinoma (108 days). This also determines its clinical characteristics, i.e., rapid disease progression and early occurrence of hematogenous metastasis, thus losing the chance of cure, and therefore poor curative effect and high mortality. We have cured some small cell lung cancer from the 1980s, and some of these cases have already entered advanced stage, but still achieved cure after careful treatment, as reported below: Han, male, 38 years old, from Zhouzhi County, Shaanxi Province, a logging worker of Ningdong Forestry Bureau. 1983, small cell lung cancer was diagnosed by pathology due to dry cough. He was given 6 cycles of chemotherapy with CONP regimen, during which he was cured with radiation therapy for 21 years until he died of cerebral hemorrhage complicated by diabetes mellitus in 2004. Xiang, a 32-year-old male from Baoji, Shaanxi Province, underwent lobectomy in a local municipal hospital in 1984 due to suspected tuberculosis and was diagnosed with small cell lung cancer in the postoperative pathology report. He was cured after 2 courses of chemotherapy with the ECHO regimen and is still alive after more than 20 years of follow-up. Ren, a 61-year-old male retired worker from Xi’an, came to our hospital in 2003 with a cough and sputum with blood, and was diagnosed with small cell lung cancer by pathology. He was given 6 cycles of EP chemotherapy with local radiotherapy plus PCI, and is still alive after 13 years of follow-up. Yin, male, 48 years old, from Guodu town, Xi’an, is a farmer. He was diagnosed with small cell lung cancer combined with superior vena cava syndrome in our hospital due to cough, shortness of breath, high difficulty in breathing, inability to lie down, and high facial swelling. After being given the EP regimen of emergency chemotherapy, the dyspnea was relieved the next day, and continued to 6 cycles of chemotherapy, with radiotherapy in between, all symptoms disappeared and the tumor completely subsided. He is alive at 7 years of follow-up. Currently, the highest survival rate after treatment for small cell lung cancer is 35% at three years (all small cell lung cancer cases) and 5% at five years (limited stage – those with tumors confined to the chest cavity). The median survival was 6 months. The four cases of small cell lung cancer in this paper achieved a cure, indicating that with careful treatment, some cases can still be cured even at advanced stages. The key is to grasp the following points: 1. increase or decrease confidence and active treatment; 2. reasonable treatment. It is to just grasp each specific case, scientific and reasonable treatment plan, mainly chemotherapy, timely with radiotherapy, and even surgery (generally not considered surgery). Here the treatment strategy is of utmost importance. Throughout the implementation of the treatment plan, both the patient and the doctor, are key factors in the cure. There are certain risks involved in the treatment, so the doctor must make careful arrangements and be courageous, and the patient must support the doctor and be brave enough to cooperate. We believe that more patients will be cured.