Inflammation and enlargement of submandibular gland can be treated with medication or surgery if necessary. 1. Drug treatment: when the submaxillary gland is inflamed and enlarged, patients can take antibiotic drugs, such as ceftazidime, amoxicillin and so on, according to the doctor’s instructions. This phenomenon is due to local duct blockage, bacterial retrograde infection, so need to take antibiotic drugs, but the treatment may cause recurrence. 2. Surgery: In order to avoid recurrence of inflammation and enlargement of submandibular gland, it is recommended to wait until the inflammation is eliminated, and then you can choose surgical treatment, to remove the foreign body through surgery, or to remove the gland. After the inflammation and enlargement of the submandibular gland, it is recommended that the patient should consult a doctor in time, give standardized treatment after a clear diagnosis, and should not ignore the symptoms and take it lightly, and the above mentioned medicines should be used under the guidance of a doctor, and should not be used indiscriminately.