Childhood lymphoma mostly occurs in children aged 5 to 12 years old, and its manifestations are not particularly obvious in early stage. Early clinical manifestations are mainly intermittent recurrent fever, fever of unknown origin, and the fever symptoms become more and more severe as time passes. Early clinical manifestations are painless, progressive lymph node enlargement or localized lump, weakness, abdominal swelling and pain, night sweating, emaciation, skin itching and other symptoms. Gradually, the swollen lymph nodes develop to fuse with the surrounding tissues and are treated with antibiotics, and anti-infective treatment has no effect but increases in size. In the early stage, sometimes the nature of pain is similar to the symptoms of acute appendicitis or acute obstruction, which also needs to be taken seriously and not to be misdiagnosed, and promptly go to hospital for examination and treatment, which requires routine blood tests, liver and kidney function tests, X-ray and CT scans, blood sedimentation, bone marrow aspiration, biopsy and other examinations. Lymphoma in children is a lesion of lymph as well as lymphatic tissue, which is divided into Hodgkin’s lymphoma and non-Hodgkin’s lymphoma, caused by virus, radiation, immunity, etc. It needs to be treated by surgery, or radiotherapy and chemotherapy. If the lymph nodes in the neck, armpits or thigh roots are swollen but not painful, this is a condition that needs to be taken seriously and promptly checked by a doctor. Usually do more aerobic exercises, run, play ball to strengthen immunity, regular work and rest, reasonable diet, maintain a good state of mind, release negative emotions, and avoid excessive exposure to rays, certain chemicals.