The inner side of the knee hurts when pressed commonly due to soft tissue infection, medial collateral ligament injury, medial meniscus injury, knee osteoarthritis, bone fracture, etc. The treatment for different conditions varies, and it is mostly divided into general treatment, medication (ibuprofen, etc.), physiotherapy (hot compresses, etc.), and surgical treatment. 1. Soft tissue infection: it can be manifested as localized redness, swelling, heat and pain. Attention to rest, can take amoxicillin and other antibacterial drugs anti-infection treatment, local hot compresses can promote the absorption of inflammation, the formation of abscesses can also be given incision and drainage. 2. medial collateral ligament injury: there is a clear history of trauma, during the recovery period, pay attention to rest, local cold compresses in the acute period, local hot compresses in the remission period, severe pain can be given to ibuprofen and other painkillers, if the ligament is badly torn, can be given to surgical suture repair. 3. Medial meniscus injury: in the acute period, rest is the main focus, local cold compresses can be given, and in remission, appropriate activities can be given to hot compresses. Diclofenac sodium and other drugs can be given, for meniscus injury is serious, can be given arthroscopic menuplasty or meniscectomy. 4. Knee arthritis: such as osteoarthritis, rheumatoid arthritis, etc., the acute exacerbation of the main rest, remission can be appropriate hot compresses, diclofenac sodium and other non-steroidal anti-inflammatory drugs, but also can be injected into the joint cavity of the sodium vitreous acid treatment. 5. Fracture: in addition to rest and braking, according to the severity of the fracture, give external fixation or cut and replace internal fixation treatment. It is recommended to go to the hospital to improve the examination, to clarify the condition, the professional physician to give appropriate treatment for the condition, the drugs need to be used under the guidance of a professional physician.