In terms of 200 mg/tablet of amiodarone, postoperative amiodarone for atrial fibrillation should be taken as one tablet three times daily for the first week, one tablet twice daily starting in the second week, and one tablet daily starting in the third week. However, the exact usage has to be chosen according to the specific situation after the operation. Moreover, amiodarone should not be taken for too long. After one month of taking amiodarone, a follow-up examination should be conducted, and the decision of whether to continue using the drug should be based on the results of the follow-up examination. Atrial fibrillation refers to irregular rapid fibrillation wave instead of regular electrical activity of the heart arrhythmia, serious cases can affect the daily life, so part of the case can choose radiofrequency ablation for treatment, and often need to routinely use amiodarone after the operation. Amiodarone belongs to class III antiarrhythmic indications, can be used for atrial fibrillation, ventricular fibrillation, ventricular tachycardia and other arrhythmias, but in the process of taking the drug can be cardiac pain, abdominal pain, thyroid abnormality and other adverse reactions. And the use of amiodarone is prohibited for those who are allergic to amiodarone, severe hypotension, circulatory failure, respiratory failure and so on. After atrial fibrillation surgery must strictly follow the doctor’s prescription medication, so as not to affect the effect of surgery or even threaten the life and health.