The painful leg pain that occurs the day after drinking is usually due to strain and strain of the leg muscles, tendons and ligaments or cold after drinking, resulting in the accumulation of sterile inflammatory lesions that stimulate the peripheral nerves around them. The following therapeutic measures should be taken to address the cause and mechanism of the disease: 1. Give the leg pain area adequate rest and avoid continued activity, otherwise it will lead to further strain on the strained and damaged area, which is not conducive to healing. 2. Be sure to pay attention to warmth and avoid getting cold, because after getting cold, it will lead to slowing down of local blood circulation and the accumulation of inflammatory metabolites will stimulate the surrounding nerves, leading to further aggravation of the pain symptoms. 3, Take oral non-steroidal anti-inflammatory and analgesic drugs, such as loxoprofen sodium and diclofenac sodium to relieve local inflammatory lesions and reduce inflammatory edema and pain. 4. Take oral Eperisone hydrochloride tablets to relieve muscle tension caused by injury and strain caused by cold. 5.Take oral Chinese medicine to activate blood circulation, relieve blood stasis, reduce swelling and pain, such as blood circulation and pain capsules, and Dazhiri capsules to increase local blood circulation and promote the absorption of inflammatory metabolites. Generally, after the above treatment, the symptoms will be significantly improved in 3-5 days.