To distinguish between common cold and novel coronavirus infection, we must first analyze the clinical history and symptoms collected from the above. The common cold is generally caused by parainfluenza virus, rhinovirus, or echovirus, coxsackievirus and so on. Secondly, the general symptoms of the cold are first sneezing, runny nose and other upper respiratory symptoms, as well as throat discomfort and sore throat, and then gradually progress, and later there may be fever, but generally do not cause much lung lesions, at most to the throat cough such as bronchitis. Of course, if it is influenza, such as influenza A and B can also cause pneumonia, but influenza A, influenza B and the new coronavirus can be directly done nucleic acid testing, now the nucleic acid test for influenza A and B is very mature, and the nucleic acid test for the new coronavirus is also available, so these can be distinguished. In addition, the new coronavirus, from the symptoms of its preliminary sneezing, runny nose, and pharyngeal symptoms are not very typical, generally after the fever will appear more quickly breathing difficulties and general weakness, which is different from the common cold. The pharyngeal symptoms of influenza A and influenza B will be more obvious, but there will also be a high fever, and also cause pneumonia, so the clinical symptoms and medical history to ask clear and then do the appropriate examination, or better distinguish.