Is it safe to use hormones in the nasal cavity? At present, allergic rhinitis and other nasal diseases, the most commonly used drugs for the nasal cavity local use of glucocorticoids, glucocorticoids have obvious anti-inflammatory, anti-allergic and anti-edema effect, can promote the lesions of the nasal mucosa back to normal. Many patients are afraid of hormones, and have the feeling of “talking about hormones”, because the hormones we usually contact with mostly refer to the systemic use of glucocorticoids (injections or oral), and the side effects are not to be underestimated. The hormones used in the nasal cavity are localized drugs, and the dosage used is very small compared to systemic drugs, so the safety of nasal hormones is very high. Of course, it does not mean that nasal hormones do not have any side effects, a small number of patients may have the adverse effects of nasal dryness and nosebleed, which can be mitigated by the use of some nasal oils, such as vitamin AD drops. In the clinic, I also found that there are very few patients in the long-term use of nasal hormones after the septum perforation, which is mostly related to the incorrect method of nasal spray. How to use nasal glucocorticosteroids correctly? First of all, the patient should master the correct method of nasal spraying, when spraying the drug, usually use the left hand to spray the right nose, the right hand to spray the left nose, so that the drug can better enter the deep part of the nasal cavity, so as to better play the effect of the drug, and to a large extent to avoid the occurrence of septum perforation due to the prolonged spraying of the drug to the middle of the nasal cavity; Secondly, in the number of times of the drug is generally speaking, once a day, spray 2 samples of the drug for each nostril, usually recommended at 8:00 in the morning, and then spray 2 slices for each nostril. Secondly, in terms of frequency of administration, it is usually recommended to use the medication once a day, with 2 sachets per nostril, at around 8:00 a.m. in the morning, when the level of adrenocorticotropic hormone normally secreted by a person is low and the concentration of inflammatory mediators is high, which not only can better suppress the inflammatory response, but also minimize the adverse effects of the nasal hormones. Doctors may also increase the number of medications according to the severity of allergic rhinitis, the mucosa of the operative cavity after nasal polyp surgery, if the severity of allergic rhinitis or the mucosal edema after surgery is more serious, more vesicles or granulations, it can be appropriately increased to 2~3 sprays per day; In addition, in terms of the cycle of the use of nasal hormone medication, generally speaking, it should be used for 2~3 months in a row, 1~2 times a day, and then according to the symptomatic Control and examination of the situation gradually reduce the number of times the drug, such as switching to every other day 1 time, until the mucosa back to normal after the change to 2 times a week after the amount of prophylactic drugs.