For some patients, general gastroscopy is more or less unpleasant experience, often with nausea, vomiting, abdominal pain and other symptoms, and even elevated blood pressure, inducing the occurrence of angina and other complications, bringing certain heart barriers to the patient’s heart; or some patients hear the gastroscopy on the fear of refusing the examination, and even some patients say: “rather to his life Some patients even say: “I’d rather have his life than that mirror”, so that the condition is not timely examination and delayed diagnosis and treatment, resulting in lifelong regret. In the 1990s, some countries in Europe and the United States began to painless gastroscopy, that is, the use of sedative anesthetics before the examination, thereby greatly improving the tolerance of the subject, so that gastroscopy becomes easy and painless. With the continuous improvement of living standards in China, patients’ requirements for medical treatment have become higher and higher. In recent years, many hospitals in China have also carried out painless gastroscopy with propofol intravenous anesthesia, and the results are very satisfactory, but this service has undoubtedly increased the economic burden of patients. However, pain has been internationally regarded as the fifth vital sign of human beings, so in hospitals and regions with conditions, especially in economically developed regions, painless gastroscopy is a technology worth promoting, reflecting the human-centered concept and reducing patient pain to meet the requirements of patients with different needs, so that more patients can receive gastroscopy and treatment in a timely manner.