The three bilirubin tests include total bilirubin, direct bilirubin and indirect bilirubin, which are elevated while other indicators are normal, probably due to excessive consumption of animal blood products before the test, or due to hemolysis during the blood test. During this period, patients should pay attention to diet, exercise and rest to avoid affecting the test results. If the results are still high after rechecking, it is necessary to consider whether it is caused by diseases, such as liver disease, hemolytic disease, biliopancreatic disease, etc. 1. liver disease: for example, fatty liver, alcoholic liver, hepatitis B, and cirrhosis of the liver, both indirect bilirubin and direct bilirubin are elevated. In the case of fatty liver, in addition to the three elevated bilirubin, most of them can be accompanied by obesity, hypertension, hyperlipidemia, etc. First of all, we need to control weight, exercise reasonably, and at the same time take statins or fibrates and other drugs for treatment as prescribed by the doctor. In the case of alcoholic liver, patients usually have the habit of drinking a lot of alcohol for a long time, so it is recommended to stop drinking in time and take liver-protective drugs as prescribed by the doctor for treatment. In the case of hepatitis B, patients often have symptoms such as dizziness, weakness and discomfort in the liver area, and need to take antiviral drugs such as lamivudine and entecavir as prescribed by the doctor, while interferon drugs can be given to enhance the therapeutic effect. For patients with cirrhosis, it is recommended to follow medical advice for comprehensive assessment and then perform drug or surgical treatment; 2. Hemolytic diseases: for example, neonatal hemolytic disease, acute transfusion reaction, etc., with elevated indirect bilirubin, which is considered to be related to prehepatic factors. If it is neonatal hemolytic disease, the child may have symptoms such as jaundice and anemia, and treatment such as albumin and immunoglobulin can be given. If it is an acute transfusion reaction, the patient may show high fever, chills, allergy, etc. The transfusion should be stopped immediately, physical cooling should be given to patients with high fever, and intubation should be given to patients with severe allergy or even respiratory distress. 3. Biliary and pancreatic diseases: such as gallstones, bile duct cancer, pancreatic head cancer, etc., direct bilirubin elevation is predominant, and obstructive jaundice is usually present. For these three diseases, surgery is generally recommended, and in case of cancer, radiotherapy and chemotherapy are also given depending on the situation. If the patient has three elevated bilirubin tests and other indicators are normal, he needs to promptly review liver function and combine with liver imaging, such as CT and ultrasound, to determine the specific cause and give targeted treatment.