Chest pain after drinking alcohol may be caused by the following two factors: 1. It may be acute heart disease caused by angina pectoris or acute myocardial infarction, which is usually accompanied by chest tightness, palpitations, cold sweat all over the body, dizziness and other symptoms in addition to chest pain. The nature of the pain is mainly of a crushing sensation. If this happens, you must immediately go to the hospital for an electrocardiogram as well as a blood troponin test to be able to make a clear diagnosis.2. It may be a problem with the stomach, with pain in the chest, under the sternal process, usually accompanied by discomfort in the upper abdomen, with bloating, stomach pain, nausea, vomiting or exhaustion, etc., caused by the stimulation of the gastric mucosa after drinking.