Gastric distension can not flow duodenum need to implement different treatments according to different conditions, different causes, different treatment methods. Common causes include gastritis, peptic ulcer, pyloric obstruction and dyspepsia, as follows: 1. Gastritis: acute and chronic gastritis can cause gastric distension, feeling flow not to the duodenum, especially acute gastric mucosal injury is more likely to appear this symptom, can stop using the substances that damage the gastric mucosa, and at the same time give the proton pump inhibitor (omeprazole, etc.), gastric mucosal protectant (magnesium alumina carbonate, etc.) drug therapy. 2. Peptic ulcer: peptic ulcer can cause gastric distension and other symptoms, such as the combination of Helicobacter pylori infection, it is necessary to anti-Helicobacter pylori treatment at the same time as the treatment of peptic ulcer, commonly used drugs are omeprazole, bismuth potassium citrate, metronidazole, clarithromycin, amoxicillin, levofloxacin and so on. 3. Dyspepsia: dyspepsia caused by gastric distension flow can not be duodenum, can be adjusted in the diet, including food type, eating style, etc., can be to promote gastrointestinal dynamics of drugs such as mosapride tablets. 4. Pyloric obstruction: severe pyloric obstruction can be treated surgically. When the patient has symptoms of gastric distension, it is recommended to consult the gastroenterology department in time to clarify the cause of the disease, treat the cause, and use medication under the guidance of the doctor, to avoid self-medication, which will cause the disease to be delayed.