Glucose-lowering medications include oral hypoglycemic agents and injectable medications. Oral hypoglycemic drugs include biguanides, α-glucosidase inhibitors, sulfonylureas, glinides, thiazolidinediones, sodium-glucose cotransporter protein 2 (SGLT-2) inhibitors, and dipeptidyl peptidase-4 (DPP-4) inhibitors, etc. Injectable drugs include insulin and glucagon-like peptide-1 receptor agonists. Metformin among the biguanides is the first-line drug for controlling hyperglycemia in patients with type 2 diabetes mellitus and the basic drug in drug combinations. Sulfonylureas (e.g., glimepiride), glinides (e.g., repaglinide), alpha-glucosidase inhibitors (e.g., acarbose), thiazolidinediones (e.g., rosiglitazone), SGLT-2 inhibitors (e.g., dagliflozin), DPP-4 inhibitors (e.g., selegiline), glucagon-like peptide-1 agonists (e.g., liraglutide), and insulin are the main combinations of drugs. For patients with diabetes mellitus, it is recommended to consult the endocrinology department of a regular hospital and be guided by an endocrinologist.