Neonatal jaundice subsides in a bottom-up order, that is, the lower limbs subside first, followed by the abdomen, chest and finally the face. It occurs in the opposite order, with the head and face appearing first, followed by the chest, abdomen, and lower limbs. If the soles of the feet are also yellow then the baby’s jaundice must be severe, exceeding the normal value. Generally, the maximum value of jaundice in full-term babies is not more than 12.9mg/dL, and in preterm babies is not more than 15mg/dL, and if it is more than that, it is pathological jaundice. Neonatal pathological jaundice has several conditions: 1, early appearance, 24 hours after birth; 2, the degree of heavier, full-term infants more than 12.9mg/dL, preterm infants more than 15mg/dL; 3, later subside, full-term infants more than 2 weeks does not subside, preterm infants more than 3 weeks does not subside; 4, the proportion of direct bile (direct bilirubin) is high, more than the total bile (total bilirubin) of the 20%.