Bleeding at the puncture point of picc tube placement is usually related to mechanical stimulation, chemical stimulation, abnormal coagulation function and other factors. 1. Mechanical stimulation: If the needle of picc tube placement puncture is thicker, the trauma after puncture is bigger, so it will cause bleeding. It is also possible that the doctor’s skill is not skillful enough, resulting in trauma to the puncture site. Generally, no special treatment is needed, and the bleeding can be stopped after the puncture needle is withdrawn. 2. Chemical stimulation: In the picc tube placement puncture need to use the relevant agents, if the concentration of the drug is too high, the stimulation is relatively strong, may stimulate the blood vessels, thus leading to bleeding puncture point. This type of bleeding generally does not require special treatment, and can be relieved only after stopping treatment. 3. Abnormal coagulation function: If the patient’s own coagulation function is poor, the healing of the puncture point will be affected, so it will bleed repeatedly. If the amount of bleeding is small, bandage can be used to stop bleeding; if the amount of bleeding is large, it is necessary to supplement coagulation factors, such as vitamin K, the specific use of drugs should be in accordance with the doctor’s instructions. After the picc tube puncture point bleeding, please timely hospital consultation, active diagnosis and treatment. At the same time, do a good job of local care, to avoid secondary infection.