Multiple solid thyroid nodules should be taken seriously, and should be referred to the local hospital to complete the relevant examinations to determine the nature of good and bad, and then further treatment. In thyroid nodules, the presence of substantial, hypoechoic nodules with one or more of the following signs, such as microcalcifications, nodule aspect ratio>1, irregular margins, and enlarged cervical lymph nodes suggests that the nodules may be malignant. Common tests for thyroid nodules include laboratory tests, ultrasonography and imaging tests. Laboratory tests include thyroid function tests, such as serum thyroid stimulating hormone, thyroid peroxidase antibody, etc.; ultrasonography, i.e., thyroid ultrasonography; and imaging tests, such as CT, PET-CT, magnetic resonance imaging. Ultrasound-guided fine-needle aspiration biopsy is feasible when necessary to clarify the nature of the nodule. Therefore, attention should be paid to solid nodules, and relevant examinations should be completed as soon as possible to determine the nature of thyroid nodules, and treatment should be carried out under the guidance of doctors.