The risk of surgery for advanced rectal cancer varies with the patient’s physical quality and the risk of the surgery itself, and cannot be generalized. In terms of the patient’s own physical quality and the surgery itself, if the patient himself suffers from basic diseases, such as high blood pressure, diabetes, etc., the risk will be higher when he undergoes the surgery; and when the patient undergoes the surgery, the risk will be higher in the case of postoperative bleeding, adhesive intestinal obstruction and so on. If patients have strong physical condition, no underlying disease, no special condition and good recovery after surgery, the risk of late-stage rectal cancer surgery is smaller, but they still need to actively cooperate with doctors for timely treatment and improve the quality of life. Patients with advanced rectal cancer should pay attention to actively cooperate with doctors, follow doctors’ instructions to carry out radiotherapy, chemotherapy and other auxiliary treatments, at the same time, need to strengthen diet and nutrition, keep optimistic mentality, not to worry too much, pay attention to postoperative care, and if there is any discomfort, actively communicate with doctors.