Pancreatic cancer was first described by Mondiare and Battersdy, and was clinically reported in the literature by Bard and Pis in 1888. 1935, Whipple, a leading American surgeon, first reported the success of pancreatic and duodenal resection, thus establishing the surgical treatment of malignant tumors of the pancreas, duodenum and jugular abdomen. 1943, Rockeg first In 1943, Rockeg first performed total pancreatectomy. In China, Yu Wenguang was the first to report a case of pancreatic head and duodenum resection in 1954. In recent years, the incidence of pancreatic cancer has been increasing year by year, in the United States in 1988 the incidence rate was 9.0/100,000, male: female is 1.3:1. The incidence rate in Sweden is higher at 125/100,000 and has remained constant over the past 20 years. The UK and Norway have each increased by a factor of l. The standardized incidence rates in Canada, Denmark and Poland increased by more than 50% in the 1970s compared to the 1960s. As far as the site of pancreatic cancer is concerned, the head of the pancreas is still the most common site, accounting for about 70% of cases, followed by the body of the pancreas and the tail of the pancreas, and in some cases both the head and the body of the pancreas, which are diffuse lesions or multicentric lesions. Patients with diabetes have an eight-fold higher risk of developing pancreatic cancer than the general population. Researchers are further studying the intrinsic link between the two diseases. According to the latest issue of the monthly American Journal of Gastroenterology, researchers at the Mayo Clinic Cancer Center followed 2,122 patients over the age of 50 with diabetes and found that 18 of them were diagnosed with pancreatic cancer within the last three years. Compared to non-diabetic people in similar age and sex groups, the incidence of pancreatic cancer was eight times higher in diabetics. Suresh Chari, who led the study, said pancreatic cancer is difficult to detect until it has progressed to an advanced stage, and patients have little hope of survival. This study takes them a step closer to detecting early symptoms of pancreatic cancer and making early diagnosis and treatment possible. Almost all of the 32,000 Americans diagnosed with pancreatic cancer have died because of the difficulty of early diagnosis. Pancreatic cancer has become the 4th most dangerous cancer in the United States. Researchers believe that diabetes itself may be an early sign of this deadly cancer.