High bilirubin may be caused by physiological or pathological reasons, such as obstructive jaundice, hepatitis, etc. Physiological reasons are not harmful, while pathological reasons may lead to liver and gallbladder function damage. 1. Physiological causes: physiological jaundice is more common in newborns, usually there are no other uncomfortable symptoms, and it will not cause harm to the body, and it will gradually subside in a week or so. 2. Obstructive jaundice: it may be caused by bile duct stones or bile duct tumors, etc. If treatment is not taken in time, it will lead to symptoms such as yellow urine, yellow skin, yellow eyes, etc., and it will have a great impact on liver and gallbladder functions. 3. Hepatitis: for example, viral hepatitis, alcoholic hepatitis, etc. may cause elevated bilirubin, accompanied by elevated ghrelin and ghrelin, and will lead to liver function damage. The cause of high bilirubin needs to be clarified, and if it is caused by disease, the cause should be identified and treated in cooperation with the doctor.