There is no fixed four kinds of people who should not take American ginseng, but it is not suitable to take American ginseng for those who are taking medicines containing quinine, and those who have dampness-heat and solid-heat. American ginseng has the effect of clearing heat and generating fluids, replenishing qi and nourishing yin, and can be used clinically to treat prolonged cough with deficiency of lungs, low phlegm and dry cough, thirst and irritability caused by heat which injures qi and yin, and intestinal dryness and constipation caused by insufficient fluids. As there is a contraindication between American ginseng and quassia, they cannot be taken together, so it is not allowed to take American ginseng while taking medicines containing quassia. Yang deficiency, cold and dampness obstruction and Qi depression and fire, etc., all the real evidence, fire and depression of the evidence are not allowed to take American ginseng. Adverse effects of American ginseng are not precise, need to be used under the guidance of a doctor’s diagnosis, not to be taken without authorization.