The side of the nose hurts when pressed may be caused by dacryocystitis, acute nasal vestibulitis, nasal boils and so on. 1. Dacryocystitis: infection by pathogenic bacteria leads to congestion, swelling and pain in the lacrimal sac area, with obvious localized pressure and pain, and the inflammation can spread to the eyelids, root of the nose and cheeks. 2. Acute Nasal Vestibular Inflammation: Due to the irritation of the skin of nasal vestibule by purulent secretion, acute nasal vestibular inflammation will be caused, and there will be pain at the nasal vestibule, and the side of the patient’s nose may be painful when pressed. 3. Nasal boils: due to Staphylococcus aureus infection, acute purulent inflammation will occur, which will lead to nasal boils, and patients with nasal boils will have pain when the side of the nose is pressed. When the patient has the phenomenon of pain when pressed on the side of the nose, it is recommended to consult a doctor in a timely manner, to be diagnosed by a professional doctor, and to give targeted treatment.