Women before and after menopause should consider whether they are suffering from dryness syndrome if they have severe dry mouth for a long time and it is still ineffective after supplementing water, even accompanied by dry eyes, joint pain, tooth decay and loss of teeth piece by piece. Then what are the clinical symptoms that are the early manifestation of dry syndrome? Dry syndrome is an autoimmune disease characterized by invasion of exocrine glands, especially lacrimal gland and salivary gland. Dry syndrome is characterized by reduced secretion of lacrimal and salivary glands, dry keratoconjunctivitis and oral dryness. Dry syndrome can cause a severe reduction in all secretions including saliva, tears, sweat, digestive juices in the gastrointestinal tract, nasal secretions, etc. For example, a sharp decrease in saliva secretion causes dry mouth, atrophy of tongue papillae, disappearance and exfoliation of tongue coating, full mouth caries, etc.; also, a decrease in tears can cause dry eyes without tears, foreign body sensation, conjunctivitis, keratitis, and even blindness. Dryness is the significant feature of dryness syndrome, and all exocrine glands in the body can be atrophied and a series of dryness symptoms can appear. The main manifestations of this disease are dry mouth, dry eyes and wandering joint pain. Dry mouth is especially common, and often occurs in women around 50 years old. These patients mostly have wandering arthralgia, stiff joints in the morning, limited movement, and positive rheumatoid factor, but joint deformity rarely occurs. The occurrence of dry syndrome is due to the “recognition” error of the immune system in the body. As a result, all exocrine glands are destroyed, resulting in a sharp decrease in various exocrine fluids, dry mouth, dry eyes, and arthritic symptoms. To sum up, menopausal women who have dry mouth symptoms for a long time should pay more attention and observe, and if there is any suspicion, they should be checked early and should not take it lightly. Don’t let the hidden dryness syndrome take away your health!