Serum IgA is a kind of antibody, and IgA nephropathy refers to the deposition of IgA-based immune complexes in the glomerular mesangial area, etc., and there is no obvious correlation between the two.
Serum IgA is a kind of immunoglobulin or antibody in the blood, which can resist some bacteria, viruses and pathogens entering the body, and then protect the body from damage. Elevated serum IgA does not mean it will cause IgA nephropathy.
IgA nephropathy is characterized by renal biopsy immunopathology showing IgA-based immune complex deposition in the glomerular mesangial area, with glomerular mesangial cell hyperplasia and mesangial stroma increase as the basic histological changes, mainly manifested as hematuria, which may be accompanied by different degrees of proteinuria, hypertension and renal function impairment.
Clinical IgA nephropathy patients, serum IgA can be elevated, can be lowered, or can be shown as normal, and there is no obvious correlation between the two.
Patients with IgA nephropathy should go to the hospital in time and receive standardized treatment under the guidance of professional physicians.