A plus sign for trichomonas, also known as a positive trichomonas, means that trichomonas is seen in the discharge, which is a sign of trichomoniasis. If you have trichomoniasis, you will have increased vaginal discharge, a fishy odor, and itching of the vulva. It is important to treat this condition as it can be transmitted to the partner through sexual intercourse, so if there has been sexual contact in the recent past, the male partner should also be given medication. The common clinical drugs used to treat trichomonas are metronidazole, tinidazole and ornidazole, which can be used systemically or vaginally.