In females, voice change usually occurs during puberty, roughly between the ages of 10 and 15. The exact timing of voice change may vary due to individual physiological differences. It is a period of transition from childhood to adulthood, a stage of gradual development to maturity of the genitals, endocrine system, and physique. The World Health Organization (WHO) defines puberty as the period from 10 to 19 years of age. Puberty is the second peak of physical development, from the onset of secondary sexual characteristics to full physical development and sexual maturity. During this stage, the female voice also changes, usually to a lower or higher pitch. During puberty, the change in a girl’s voice varies from person to person and may not be particularly noticeable, and is mostly seen between the ages of 10 and 15. In addition to voice changes during puberty, there are other clinical manifestations, such as breast eruption, pubic hair development, accelerated growth, menarche, etc. At the same time, women’s psychological changes may occur, such as easy to be excited, impulsive, etc., family members should pay close attention to do a good job of psychological counseling. If necessary, the patient may seek medical treatment in time to receive formal psychological treatment, so as not to neglect the condition, resulting in adverse consequences.