Black rough keratinization of elbow needs to be treated according to the specific cause, such as hyperkeratosis, chronic eczema, neurodermatitis, etc., and choose the general treatment or medication, etc., after clear diagnosis. 1. Excessive keratinization: black roughness keratinization of the elbow may be due to prolonged excessive friction and prolonged extrusion, without special treatment. Patients need to do a good job of local hygiene, and then do a good job of local moisturizing, minimize friction. 2. Chronic eczema: chronic eczema on the elbow can cause local inflammation and hyperpigmentation, thus showing black rough keratinization on the elbow. Treatment can choose glucocorticoid creams such as Dinaid cream and other drugs used externally to help its exfoliation, but also need to do a good job of daily skin care. 3. Neurodermatitis: Neurodermatitis needs to be considered and mental factors, allergens and other factors related to the elbow can show black rough keratinization. Treatment can follow the doctor’s instructions to use Dinaid cream, mometasone furoate cream external, at the same time to do a good job of skin moisturizing, avoid hot water scalding. It is recommended that patients go to the hospital in a timely manner, in accordance with the doctor’s instructions to take standardized treatment, not to ignore the symptoms, take it lightly, so as not to lead to adverse consequences.