There are many possible factors that can cause pediatric cerebral palsy, and one of them is neonatal hemolytic jaundice, which is a major concern. It is understood that this is an immune reaction caused by RH blood group or ABO blood group incompatibility, which can cause neonatal immune hemolytic disease. It usually affects the normal nerve cell development and intellectual development of the child, leading to the occurrence of pediatric cerebral palsy, and in more serious cases, it can even cause severe anemia or heart failure death of the newborn. In order to avoid cerebral palsy caused by hemolysis in newborns, young couples, pregnant women and husbands should do blood group check. If the husband is type A, B or AB and the pregnant woman is type O, there is a possibility of ABO blood group incompatibility between mother and child; if the husband is RH positive and the pregnant woman is RH negative, there is a possibility of RH blood group incompatibility and characteristic antibody check should be done for early prevention and control. Once a newborn is found to have hemolytic jaundice, he should immediately go to a hospital with conditions for comprehensive treatment and, if necessary, blood exchange therapy, early detection and early diagnosis and treatment can turn the affected child into a safe one. Of course, in addition to the above causes, placental abnormalities, fetal malposition, intrauterine distress, prematurity, multiple births, birth asphyxia, neonatal hypoxic-ischemic encephalopathy, infection, trauma, cerebral hemorrhage, brain malformation, etc. may also cause cerebral palsy in children. In conclusion, the causes of cerebral palsy are very diverse and complex. Parents should pay more attention to the performance of their newborns and do the normal physical examination to detect and treat the abnormalities early. Once the child is diagnosed with pediatric cerebral palsy, early treatment should be started immediately. Because of the damage to the brain tissue, rehabilitation of children with cerebral palsy is a lifelong process. Whichever means of treatment is used is one aspect of comprehensive rehabilitation. Among them, motor training is mainly for younger children, aiming to suppress abnormal activity patterns and promote the development of normal movement; older children need to undergo necessary surgical treatment on the basis of motor training to create favorable conditions for further motor function training when the muscle-tendon joint contracture deformity restricts the improvement of rehabilitation function. From the current clinical statistics, nearly 80% of children with cerebral palsy can receive surgical treatment. However, it should be emphasized here that the scientific treatment principle for cerebral palsy is to combine surgery and rehabilitation. In particular, as children with cerebral palsy grow older, the spastic muscles will have difficulty synchronizing with the growth of the bones, resulting in various progressive deformities. Therefore, in the process of rehabilitation training, surgery should be performed on children with cerebral palsy who are eligible for surgery in a timely manner (from 2.5 to 6 years old) to ensure that the next stage of rehabilitation is carried out smoothly.