The so-called “hepatitis B two-and-a-half” refers to the five indicators of the serum immunological test for hepatitis B virus. That is: surface antigen – HBsAg, surface antibody – HBsAb, E antigen – HBeAg, E antibody – HBeAb and core antibody – HBcAb. The clinical significance of these five test results are: 1, the first positive, the remaining four negative. It means it is the late latent stage of acute hepatitis B virus infection. 2, the first three positive, the remaining three negative. It means that it is the early stage of acute hepatitis B, which is highly infectious. 3.The first, third and fifth items are positive, and the remaining two items are negative. Commonly known as “major triple positive”, this situation indicates that it is acute and chronic hepatitis B. At this time, the virus is actively replicating and highly contagious. 4, the first five positive, the remaining three negative. This means that it is acute and chronic hepatitis B. 5.The first, fourth and fifth items are positive, and the remaining two items are negative. Commonly known as “small three positive”, indicating acute and chronic hepatitis B, but less infectious. 6, the fifth positive, the remaining four negative. This means that the person is a recessive carrier of the hepatitis B virus or is in the window of infection, and also means that he has been infected with the hepatitis B virus. 7.The fourth and fifth items are positive, and the remaining three items are negative. It means that the person is recovering from acute hepatitis B virus infection, or has been infected with hepatitis B virus. 8.The second, fourth and fifth items are positive, and the remaining two are negative. It means that it is the recovery period of hepatitis B and has immunity. 9.The second and fifth items are positive, and the remaining three are negative. It means that the person has recovered from hepatitis B vaccination or hepatitis B virus infection and has immunity.