Hormones generally refer to glucocorticosteroids. Long-term application of glucocorticosteroids and sudden discontinuation of the drug will have some uncomfortable reactions called withdrawal syndrome. The main uncomfortable reactions are as follows: a. Symptoms similar to hyperalgesia, such as fatigue, weakness, poor nasal function, poor mental health, and in severe cases, adrenal cortical crisis may occur. Second, the body has poor resistance and stress capacity, and is prone to colds, infections and other diseases. Third, there may be a drop in blood pressure and blood glucose. If diabetic patients stop using hormones without timely reduction of glucose-lowering drugs, serious hypoglycemia may occur. Fourth, when long-term application of glucocorticosteroids is suddenly discontinued or reduced too quickly, the original disease may recur or worsen, and a large amount of hormones will be taken again, so hormone discontinuation should be carried out in gradual reduction.