Lateral knee pain can be treated by general treatment, physical therapy, medication and surgery according to the cause of the disease. There is no fast recovery in the clinic, and it may be related to lateral collateral ligament injury, osteoarthritis, lateral meniscus injury and other reasons. 1. Lateral collateral ligament injury: the lateral collateral ligament is located on the outside of the knee joint and has the function of stabilizing the joint, which will cause pain on the outside of the knee when injured. After the injury, pay attention to rest, you can apply cold compresses during the acute injury period and hot compresses during the recovery period. Mild injury can be fixed with plaster or brace, serious injury requires surgical repair and reconstruction treatment. 2. Osteoarthritis: it is caused by degenerative joint lesions, which will cause degenerative damage of articular cartilage and secondary osteophytes, and also cause pain on the outside of the knee. Usually pay attention to rest, can apply non-steroidal anti-inflammatory drugs, such as celecoxib, etc.; can also be performed heat therapy, microwave and other methods of treatment. At the later stage of the disease, if there is activity disorder, artificial joint replacement is feasible. 3. Lateral meniscus injury: meniscus is divided into medial meniscus and lateral meniscus, lateral meniscus injury will also cause lateral knee pain. After the injury, we should pay attention to rest, can be in the acute period of cold compresses, hot compresses in the recovery period; mild injuries can be treated conservatively, serious injuries need surgical treatment, such as arthroscopic meniscoplasty, suture surgery, and so on. There are other causes of lateral knee pain, such as lumbar disc herniation, etc., if the persistence of non-relief, it is recommended to consult a doctor in a timely manner, improve the examination to clarify the cause of the disease, and comply with the doctor’s instructions for targeted treatment, and do not self-medication, so as not to delay the condition.