The first dose of hepatitis B vaccine is usually given to newborns within 12 hours of birth, the second and third doses are given at full term and six months, and the effectiveness of the vaccination is checked at eight months of age. Both newborns and adults without hepatitis B antibodies need hepatitis B vaccination. After receiving hepatitis B vaccination, the body can produce hepatitis B antibodies, which can play a role in preventing hepatitis B. Newborns need to be vaccinated against hepatitis B within 12 hours of birth, at full term and at 6 months of age, respectively, and quantitative hepatitis B antibody tests are done at 8 months of age to determine the effectiveness of the vaccination. As time lengthens, the titer of hepatitis B antibody gradually decreases. At this time, hepatitis B vaccination is also needed to raise the titer of hepatitis B antibody and improve the resistance to hepatitis B. In addition, patients with colds, fever, hepatitis, acute and chronic serious diseases, or those who are allergic to hepatitis B vaccine are prohibited from receiving hepatitis B vaccination.