Frequent heartburn and acid reflux is mainly caused by excessive secretion of stomach acid, which may be due to chronic gastritis, gastroesophageal reflux, peptic ulcer and other diseases. 1. Chronic gastritis: it may be caused by Helicobacter pylori infection, autoimmune, age factors, etc. These factors can stimulate the stomach wall, the phenomenon of excessive secretion of gastric acid, resulting in frequent heartburn and acid reflux phenomenon. 2. Gastroesophageal reflux (GERD): a disease in which the contents of the stomach and duodenum reflux into the esophagus, mouth and lungs, causing discomfort and/or complications. Its pathogenesis is related to the decrease of esophageal clearance and the decrease of the barrier function of the esophageal mucosa. The above symptoms may occur due to acid reflux. 3. Peptic ulcer: refers to the ulcers that occur when the mucosa of the gastrointestinal tract is digested by gastric acid and pepsin, which is a comprehensive result of one or more invasive factors that damage the mucosa more than the mucosa’s ability to resist damage and repair itself. The phenomenon of frequent heartburn and acid reflux occurs due to excessive secretion of gastric acid. In addition, frequent heartburn and acid reflux can also be seen in other diseases, it is recommended that patients go to the hospital in time to avoid delay.