There is no definite clinical conclusion about the time of development of chronic gastritis to gastric cancer, usually the pathology and clinical manifestations are different, and the possibility of developing into gastric cancer is also different. In case of non-atrophic gastritis, the prognosis is generally good and most of them will not develop cancer as long as they are actively and correctly treated. In case of atrophic gastritis, if there are opportunities for cancer such as chemosis and heterogeneous hyperplasia, and there is no active treatment, the development of gastric cancer is a long-term process, which may take several years to several decades, and the specific situation varies from individual to individual. The causes of chronic gastritis usually include Helicobacter pylori infection, gastro-duodenal reflux, as well as drugs and toxins, autoimmunity, etc. If the lesions are severe or not taken seriously and not treated, the gastric mucosa becomes severely diseased and such patients are at risk of cancer. Especially if the patient is a middle-aged or elderly person and presents with belching, acidity, mid-upper abdominal discomfort, fullness, dull pain, or pernicious anemia, general debility, or weight loss, he or she needs to be alert and seek timely medical examination for precancerous and cancerous lesions. Patients with chronic gastritis and prone to recurrent attacks are advised to undergo regular examinations, including gastroscopy, histological examination, laboratory tests, etc. If patients have H. pylori infection, they need to eradicate H. pylori through quadruple therapy under the guidance of a doctor. If patients with severe chronic gastritis can undergo microscopic treatment and strict regular review. In addition, there are more causes for the occurrence of gastric cancer, patients should also avoid eating pickled, smoked and moldy foods in their diet. Long-term alcohol consumption, smoking or poor mood may also be the cause of cancerous or direct cancerous changes of chronic gastritis, which should be avoided as much as possible.