Melasma at the corners of the eyes can be improved or removed through general treatment, medication and physical therapy. 1. General treatment: Avoid sunlight exposure, choose and use skin care products correctly, maintain a healthy work schedule, adjust daily life style, avoid taking hormone or photosensitive drugs, or drugs that cause hormone level changes. 2. Medication Topical medication: local decolorizers can be used, such as 2%-5% hydroquinone cream, 15%-20% azelaic acid cream and other medications. Oral medication: vitamin E can resist lipid peroxidation, oral vitamin C can inhibit melanin synthesis. Glutathione and vitamin C can reduce melanin production. If melasma is more severe, vitamin C can be given intravenously. It is used in serious condition. 3. Laser treatment: Picosecond and ultra-picosecond lasers have certain therapeutic effect on melasma, but it needs several times of treatment. Patients who have the will to improve melasma at the corner of eyes are suggested to go to regular medical hospitals and avoid unauthorized medication to avoid adverse reactions.