In recent years, with the development of society, people’s living habits and eating habits have also undergone great changes, the original eat light diet has become heavy, many of those who did not eat chili peppers in the past also often eat, more and more people do not eat breakfast, so the occurrence of disease also has a new change, the incidence of gallstones more and more people, the incidence of higher and higher. There are many types of gallstones: 1. Simple ones, such as simple gallbladder stones, are treated according to the function of the gallbladder by choosing biliary stone extraction or gallbladder removal (our hospital is the earliest and the most hospitals in China to carry out biliary stone extraction). Huang Gang, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Guangzhou Medical University 2. Simple common bile duct or/and common hepatic duct stones, minimally invasive choledochotomy for stone extraction or open laparotomy – the current surgical method in most hospitals. 3.Complex intra- and extra-hepatic bile duct stones, open or laparoscopic stone extraction – the open method is currently used in most hospitals, but it is more difficult to get all the stones and requires multiple surgeries, which brings multiple blows to patients and families. For the treatment of stones in the above 2 and 3 cases, our hospital has been using laparoscopic choledochotomy for more than 10 years. After researching and summarizing, our hospital has taken the treatment of gallstones to a new level and pioneered a more minimally invasive and effective stone extraction technique – percutaneous transluminal bile duct stone removal, which is used for the treatment of common bile duct or/and common hepatic duct stones, complex intra- and extra-hepatic bile duct stones, and has treated thousands of cases and received excellent We have treated thousands of cases with excellent results. This technique has been extended to the whole country. This technique is designed to remove stones from the internal and external bile ducts of the liver with minimal trauma – less traumatic than laparoscopy, requiring only a small incision of less than 5 mm in the abdominal wall (laparoscopy requires 3-4 incisions of 5 mm to 1 cm) and without incision of the common bile duct or common hepatic duct.