Tingling of the hands and arms while sleeping at night can be caused by compression of the arms, cervical spondylosis, cerebral ischemia and other reasons. There are more reasons for numbness of the hands and arms when sleeping at night, and the most common one is caused by improper sleeping posture. The patient’s wrist and arm are improperly positioned, resulting in the sensory nerves and blood vessels of the upper extremities being compressed, thus inducing the manifestation of numbness of the hand and arm. As long as the upper limbs are stretched after waking up and the compression is lifted, the symptoms of numbness will be gradually relieved. Cervical spondylosis may also lead to numbness of the upper limbs, mainly caused by the compression of the cervical nerve roots and then spread to the brachial plexus nerve. There may also be neck pain, stiffness and other discomforts. Tests such as an MRI of the cervical spine can be done to help diagnose this. It is also important to be alert to the possibility of cerebral ischemia causing numbness in the upper extremities during sleep. Especially people with combined hypertension, diabetes, coronary heart disease are prone to sudden onset of cerebrovascular disease, such as acute cerebral infarction, transient ischemic attack, etc., due to cerebral vascular obstruction caused by cerebral tissue ischemia and hypoxia. In addition to causing numbness of the upper limbs, it may also cause hemiplegia, slurred speech, and even life-threatening. If the numbness of the upper limbs recurs during sleep or fails to be relieved after getting up, it is recommended to go to the hospital for further treatment. It is recommended to go to the hospital in time to further clarify the cause of the disease and give targeted treatment.