The feeling of blockage in the middle of two collarbones can be caused by huge tumor of thyroid gland, esophageal space-occupying lesion, gastroesophageal reflux, allergy and other factors. 1. Huge tumor of thyroid gland: Huge tumor of thyroid gland can compress the trachea and esophagus in the neck and cause local narrowing, which will affect breathing and swallowing, and may cause foreign body sensation such as blockage. 2. Esophageal space-occupying lesions: Esophageal tumors and other space-occupying lesions occurring in the esophagus may cause foreign body sensation when swallowing after eating, and the compression of the trachea by the tumors may affect breathing, causing poor breathing and the discomfort of congestion. 3. Gastroesophageal reflux: Gastroesophageal reflux is the reflux of food and gastric acid in the stomach after eating, which can lead to the production of foreign body sensation, blockage and stuffiness in the esophagus and throat and other parts of the body. 4. Allergy: As the body is allergic to certain foods, it can also lead to allergic reactions after eating, resulting in discomfort such as difficulty in breathing and localized congestion. 5. Other factors: If no organic lesions are found after examination, the discomfort such as stuffiness can be related to emotional and psychological factors, and psychological counseling and other treatments are needed. When the middle of the two clavicles feel blocked when eating, you need to consult a doctor in time, under the guidance of specialists to actively carry out appropriate treatment, which will help to alleviate the discomfort symptoms as soon as possible.