Currently there are five major categories of drugs for hypertension, the first category is ACEI, ARB; the second category is beta-blockers; the third category is calcium antagonists; the fourth category is diuretics; the fifth category is less used, called alpha-blockers. Generally speaking the first four drugs are recommended as a class in the current guidelines, but for some special populations, there may be some differences, such as diabetic patients, may be preferred to ACEI, ARB; the elderly may apply more calcium antagonists and diuretics; young people whose heart rate is more significantly accelerated, may use some beta-blockers. Generally single drug use, will not repeatedly increase the dose inside a particular drug. But for some blood pressure is difficult to control, may be used in combination. Some hospitals may have a hypertension clinic, so this kind of patients need long-term blood pressure monitoring, long-term follow-up at the clinic, their own hypertension diary, and regular optimization of drug regimens.