Staying up late can have many adverse effects on patients with coronary heart disease, and can significantly affect the prognosis of patients with coronary heart disease. Coronary heart disease is coronary atherosclerotic heart disease, in the original myocardial cells in a state of ischemia, stay up late can lead to plant nerve dysfunction, into the night sympathetic nerves should be inhibited, because stay up late but has been in a state of excitement, it is easy to cause coronary vasospasm, myocardial ischemia, angina attack, and even acute myocardial infarction or sudden death. People who stay up late often have irregular diets, often supplemented with late-night snacks plus sedentary is easy to gain weight combined with abnormal glucose and lipid metabolism, which can aggravate the occurrence of coronary atherosclerosis. The endocrine disorders caused by staying up late, insufficient blood supply to the brain, memory loss, irritability, irritability, etc. can increase the burden on the heart, aggravate myocardial ischemia, and seriously affect the recovery of patients with coronary heart disease. It is recommended that patients with coronary heart disease must develop a good work and rest schedule, early to bed and early to rise in order to be well.