Cranial defect is a common clinical secondary disorder. Cranial defects may remain after many craniotomy procedures in neurosurgery, such as after traumatic brain injury, brain tumor surgery, brain hemorrhage, etc. The occurrence of cranial defects can be very harmful to patients, both physically and psychologically. The area of skull defect without the protection of hard shell will be very unsafe, the impact of external sharp objects may directly injure the brain tissue, and even directly endanger the life; skull defect is very harmful to the appearance of aesthetics, local serious collapse, or some expansion, the appearance looks very frightening, some patients will have some psychological barriers, and even low self-esteem depression; in addition, after the skull defect, the stable closed cranial cavity is destroyed In addition, the skull defect destroys the stable closed cranial cavity environment, which affects the cerebrospinal fluid circulation and cerebral blood operation, and can produce a series of neurological symptoms; in addition, there is no skull locally, only a layer of scalp cover, below is the brain tissue, some people can see the brain fluctuate from the outside, and some people also ask whether the soft brain of the exposed part of the skull defect can be touched. So can the soft brain of the exposed part of the skull defect be touched or not? In fact, the brain is not directly exposed, there is at least one layer of scalp protection outside the brain, so you can touch it, you can caress it and touch it gently. But can not collide, can not bump, especially to pay attention to protection, to prevent the impact of external sharp objects. Touching is still possible, after all, you still have to wash your hair. Of course, it is normal for patients to worry about whether the soft brain of the exposed part of the skull defect can be touched, because there may be an accident if they are not careful. Therefore, for patients with cranial defects, those who meet the surgical indications should undergo cranial repair as soon as possible, and it will be okay to touch it after the repair.